Prolonged Q-T interval following astemizole overdose.
نویسندگان
چکیده
Astemizole overdose has been reported to cause torsades-de-pointes and in the present case it caused prolongation of the Q-T interval. Astemizole overdoses should be managed in a similar way to overdose with other cardiotoxic drugs.
منابع مشابه
Drug-Induced QT Prolongation as a Result of an Escitalopram Overdose in a Patient with Previously Undiagnosed Congenital Long QT Syndrome
We present a case of drug-induced QT prolongation caused by an escitalopram overdose in a patient with previously undiagnosed congenital LQTS. A 15-year-old Caucasian female presented following a suicide attempt via an escitalopram overdose. The patient was found to have a prolonged QT interval with episodes of torsades de pointes. The patient was admitted to the telemetry unit and treated. Des...
متن کاملTorsade de pointes after astemizole overdose.
from that among normal controls and patients with osteoarthritis. Immobility per se does not seem to be a primary factor as the patients with osteoarthritis did not show an increased prevalence compared with the control group. Certain medical conditions, including pure iron deficiency, uraemia, pregnancy, gastrectomy, and carcinoma, are associated with the syndrome, providing potential clues ab...
متن کاملSuxamethonium-induced cardiac arrest as an initial manifestation of Duchenne muscular dystrophy.
prolapse and prolonged Q-T interval. Can. Anaesth. Soc. J., 26, 424. Medak, R., and Benumof, J. L. (1983). Perioperative management of the prolonged Q-T interval syndrome. Br. J. Anaesth., 55, 361. Orwitz, S., Pratilas, V., Pratila, M. G., and Dimich, I. (1979). Anaesthetic considerations in the prolonged Q-T interval syndrome (LQTS): A case report. Can. Anaesth. Soc.J., 26, 50. Wig, J., Bali, ...
متن کاملToxic Leukoencephalopathy and Delayed Neuropsychosis after Opioid Overdose
First time neuro-psychiatric disorders in the emergency department present a challenging and broad differential. Physicians often anchor on recent substance abuse as a possible cause of acute mental status change. Overlooked, however, is the occurrence of delayed sequelae as a result of a severe intoxication. This article describes the occurrence of neurologic injury at a delayed interval follo...
متن کاملTransgenic mice overexpressing human KvLQT1 dominant-negative isoform. Part II: Pharmacological profile.
OBJECTIVE The acquired long QT syndrome results most often from the action of I(Kr) blocking-drugs on cardiac repolarization. We have evaluated a transgenic (TG) mouse (FVB) overexpressing a dominant-negative KvLQT1 isoform, as an in vivo screening model for I(Kr) blocking drugs. RESULTS In TG mice, six-lead ECGs demonstrated sinus bradycardia, atrioventricular block, and QTc prolongation. Va...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Archives of emergency medicine
دوره 6 1 شماره
صفحات -
تاریخ انتشار 1989